Searchable abstracts of presentations at key conferences in endocrinology

ea0090ep47 | Adrenal and Cardiovascular Endocrinology | ECE2023

Primary hypoadrenalism and thyroiditis in metastatic renal carcinoma in Pembrolizumab (PD-1inhibitor) and Axitinib (VEGFR inhibitor) therapy

Lio Serafino , Paolello Concetta , Lamon Stefano

The association of immune checkpoint inhibitors (ICIs) and tyrosine kinase inhibitors (TKIs) are widely and to with good effect used in the treatment of many neoplasms. Much evidence of endocrine side effects has been reported for both ICIs and TKIs especially to the pituitary and thyroid functions; however, there are few records of primary adrenal insufficiency. We report the case of a 44-year-old soldier, examined for elevated hematocrit findings. Abdominal ultrasound and th...